Taylon Nichelle Celestine, 22, of Georgia, then allegedly shot two drivers before being arrested and charged with attempted murder.
Within 8 kilometres, she fired into a passing car several times, spraying auto glass and grazing the driver in the arm, Florida Highway Patrol said in a statement.
She then allegedly fired at a second vehicle, hitting the driver in the neck.
The driver was injured and treated at a hospital.
Troopers stopped the woman after she drove for about 26 kilometres and allegedly found her with an AR-15 rifle and 9mm handgun.
She was arrested and booked into the Holmes County jail.
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She was charged with attempted murder, aggravated battery with a deadly weapon and improper discharge of a firearm.
Florida Highway Patrol didn’t provide details about bail.
